Higher oxygen saturation targets did not improve growth and neurodevelopment in extremely preterm infants.
نویسنده
چکیده
*Information provided by author. MAIN RESULTS Analysis was by intention to treat. The groups did not differ for growth outcomes or major developmental abnormalities (table), or worst retinopathy (p = 0.34). However, the higher target group had higher rates of dependence on supplemental oxygen at 36 weeks PA (table) and spent more days on oxygen (median 40 v 17.5 d, p,0.001) than those in the standard target group.
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BACKGROUND The clinically appropriate range for oxygen saturation in preterm infants is unknown. Previous studies have shown that infants had reduced rates of retinopathy of prematurity when lower targets of oxygen saturation were used. METHODS In three international randomized, controlled trials, we evaluated the effects of targeting an oxygen saturation of 85 to 89%, as compared with a rang...
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عنوان ژورنال:
- Evidence-based nursing
دوره 7 2 شماره
صفحات -
تاریخ انتشار 2004